Dr. Gabe Mirkin on Fitness, Health and Nutrition

Chat with Dr. Mirkin’s AI research assistant about health issues that are discussed on the site

Eat and Sleep to Recover from Intense Exercise

Eat and Sleep to Recover from Intense Exercise

Top endurance athletes use hydration, nutrition, and sleep to help them recover from intense exercise. When you exercise for endurance, you use up glycogen, the sugar that is stored for energy in your muscles, and you damage muscle fibers.

Sylvester Graham: White Flour is a Sin

Sylvester Graham: White Flour is a Sin

Two hundred years ago, Reverend Sylvester Graham was treated by the scientific community as a nut because he claimed that white flour, meat and alcohol were poisons and that obesity was a sin. He inspired the development of graham flour, graham bread and graham crackers, vegetarian diets and prohibition of alcohol. He had no knowledge of nutrition, and vitamins had not even been discovered, so he was really a prophet.

Sylvester Graham: White Flour is a Sin

Mark Shields and Kidney Failure

Mark Shields was a political columnist, a television commentator, and an election campaign advisor to numerous democratic candidates. He was a regular commentator and analysist on the PBS NewsHour for 32 years from 1988-2020. He was one of CNN’s Capital Gang for 17 years from 1988-2005, and was a regular on Inside Washington on PBS and ABC until the show ended in 2013. Shields died from kidney failure at age 85, on June 18, 2022.

A High-Fiber Diet May Help to Prevent Dementia

A High-Fiber Diet May Help to Prevent Dementia

Researchers followed more than 3500 Japanese adults, 40-64 years of age, for 20 years and found that those who ate lots of dietary fiber were at reduced risk for developing dementia. The study found that those who ate the most soluble fiber had the lowest incidence of dementia.

Colorectal Cancer Remission with Immune Checkpoint Inhibitor Drugs

Colorectal Cancer Remission with Immune Checkpoint Inhibitor Drugs

Fourteen patients with “mismatched-repair” colorectal cancers were given a drug called dostarlimab every three weeks for six months, and follow-up after two years found that none of the patients had any remaining evidence of cancer. This is an incredible result because all patients had complete remission and none suffered serious reactions to the drug.

Eat and Sleep to Recover from Intense Exercise

Exercise to Reduce Muscle Loss and Inflammation

Women and men who exercise regularly have larger and stronger hearts, and greater endurance and strength, than those who do not exercise regularly. Their muscles are stronger and more coordinated.  We can all expect to become weaker as we age, but you can markedly delay this inevitable loss of muscle strength by having a regular exercise program and following the same anti-inflammatory lifestyle rules that are recommended to help prevent heart attacks, arthritis and many other diseases. 

A High-Fiber Diet May Help to Prevent Dementia

New Drugs May Treat Obesity

On May 13, 2022, the U.S. Food and Drug Administration approved tirzepatide (Mounjaro), from Lilly, for the treatment of type 2 diabetes. The drug has not been approved for weight loss, but so far studies show that tirzepatide with a weight loss diet causes significant weight loss in diabetics and sent 50 percent of them into remission as long as they kept taking the drug. The most recent study found that 63 percent of 2,539 obese, non-diabetic adults who were put on a weight loss diet and received tirzepatide once a week achieved at least 20 percent body weight reduction in 72 weeks.

Lifestyle Changes to Lower Blood Pressure

Lifestyle Changes to Lower Blood Pressure

A study of 14,392 individuals with high blood pressure, followed for 5-10 years, found that those who adopted a healthful lifestyle along with taking medication had a much lower risk for suffering heart attacks and lived significantly longer than those who treated their high blood pressure just with drugs.

Colorectal Cancer Remission with Immune Checkpoint Inhibitor Drugs

Healthful Habits Reduce Risk for Dementia

The American Heart Association promotes a list called “Simple 7” as a reminder of the lifestyle habits that can help to prevent dementia and heart attacks. This “Simple 7” list has been used in a 30-year study of 11,561 people (average age 54), with 2234 who developed dementia during the study period.

Colorectal Cancer Remission with Immune Checkpoint Inhibitor Drugs

Colon Cancer Associated with Sugared Drinks and Foods

The largest prospective study yet of 121,111 adult health professionals in the Nurses’ Health and Health Professionals Follow-Up Studies found 2733 cases of colon-rectal cancer, with 901 deaths. Sugar-sweetened beverages were associated with significantly increased risk for suffering and dying from colon cancer.